Abstract:
"With input from the members of the Board of Reviewing Editors and editorial staff, Science Signaling
puts the spotlight on the hottest signaling research of 2012. The
connection between signaling and metabolism continues to be an important
area. Signaling breakthroughs in cancer, immunology, developmental
biology, neuroscience, and microbiology all made the list. Structural
and molecular insights into signaling proteins and networks are also
beginning to not only yield potential therapeutic targets but also lead
to successful efforts between synthetic biologists and clinicians in the
treatment of cancer. "
M. B. Yaffe, N. R. Gough, 2012: Signaling Breakthroughs of the Year. Sci. Signal. 6, eg1 (2013).