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Wednesday, August 18, 2010

Article Most Likely to Change Clinical Practice - Week Ending August 13, 2010


CDC Releases 2010 Recommendations on Prevention and Control of Influenza
 
The Centers for Disease Control (CDC) Advisory Committee on Immunization Practices (ACIP) has released recommendations for 2010 on the prevention and control of influenza. In 2009, annual influenza vaccination was recommended for high-risk groups; routine vaccination of healthy nonpregnant adults aged 19-49 years was not recommended. The 2010 recommendations expand routine influenza vaccination to all persons aged 6 months and older, including healthy nonpregnant adults aged 18-49 years, and provide information regarding recently approved vaccines (Fluzone High-Dose, Fluarix and Afluria). CDC now recommends two doses of seasonal influenza vaccine in children aged 6 months to 8 years with no history, or only one dose, of seasonal influenza vaccine or with no or uncertain history influenza A (H1N1) 2009 monovalent vaccine (regardless of previous influenza vaccine history). It is also noted that the seasonal influenza vaccine now includes the A/California/7/2009 (H1N1)-like virus (derived from a 2009 pandemic influenza A (H1N1) virus), eliminating the need for a separate 2009 pandemic influenza A (H1N1) vaccination (MMWR Recomm Rep 2010 Aug 6;59(RR-8):1 full-text). The Food and Drug Administration has approved the vaccines for the 2010-2011 influenza season (FDA Press Release 2010 Jul 30). Vaccination should be given as soon as the 2010-11 seasonal influenza vaccine is available. If the 2010 seasonal vaccine is delayed, monovalent H1N1 2009 vaccine may still be of use (CDC 2010 Jul 6).

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